Spontaneous skeletal deformities in the Zebra Danio (Brachydanio rerio) bred for fish toxicity tests |
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| Authors: | R D Piron |
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| Institution: | Emironmental Safety Division, Unilever Research Laboratory, Colworth House, Sharnbrook, Bedfordshire, England |
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| Abstract: | Zebra Danio ( Brachydanio rerio , Hamilton-Buchanan) tropical fish are easily maintained and bred under laboratory conditions; procedures for maintenance and breeding are described. Intensive inbreeding of this fish gave rise to a high incidence of spontaneous skeletal deformities which appear to reflect a genetic defect rather than an environmental stimulus. This finding casts doubt on the suitability of the Zebra Danio for fish toxicity testing. |
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