Arylaminoethyl amides as inhibitors of the cysteine protease cathepsin K-investigating P1' substituents |
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Authors: | Altmann Eva Green Jonathan Tintelnot-Blomley Marina |
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Affiliation: | Arthritis & Bone Metabolism Therapeutic Area, Novartis Pharma AG, CH-4002, Basel, Switzerland, eva.altmann@pharma.novartis.com |
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Abstract: | Modeling, synthesis and in vitro activities of a series of arylaminoethyl amide based inhibitors of the cysteine protease cathepsin K are described. |
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