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Nasal allergy to fungi in guinea pigs
Authors:H. Bouziane  J. P. Latgé  M. C. Prévost  L. G. Chevance  S. Paris
Affiliation:(1) Unité de Mycologie, Institut Pasteur, 25 rue du Dr. Roux, F-75724 Paris, Cedex 15, France;(2) Station Centrale de Microscopie Electronique, Institut Pasteur, 25 rue du Dr. Roux, F-75724 Paris, Cedex 15, France
Abstract:Sensitized guinea pigs produced specific IgG and IgE antibodies toward Cladosporium and Alternaria. In presence of fungal extracts, nasal mast cells degranulate. Ultrastructural modifications of the cells during degranulation have been established. The ciliary epithelium and the ciliary beating are not affected by fungal allergens.
Keywords:allergy  Cladosporium  Alternaria  mast cell
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