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Bacteriocin-Related Siblicide in Clinical Isolates of Enterococci |
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| Authors: | Yun-Chan Hwang Susan E. Flannagan Don B. Clewell Christine M. Sedgley |
| Affiliation: | 1. Department of Cariology, Restorative Sciences and Endodontics, School of Dentistry, The University of Michigan, Ann Arbor, MI, USA 2. Department of Conservative Dentistry, School of Dentistry, Dental Science Research Institute, Chonnam National University, Gwangju, Korea 3. Department of Biologic and Materials Sciences, School of Dentistry, and Department of Microbiology and Immunology, Medical School, The University of Michigan, Ann Arbor, MI, USA 4. Department of Endodontology, School of Dentistry, Oregon Health and Science University, 611 SW Campus Drive, Portland, OR, 97239, USA |
| Abstract: | Siblicide is a phenomenon defined in the present context as an Enterococcus strain that, while growing as a colony on solid media, exhibits an inhibitory effect on a lawn composed of the identical strain. It was shown to occur in seven clinical isolates of enterococci (one E. faecalis and six E. faecium). Four involve inhibitory anti-listerial activities consistent with class II bacteriocins, two of which appear to be up-regulated by extracellular autoinducers. |
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