Restrictive pulmonary function is more prevalent in patients with ankylosing spondylitis than in matched population controls and is associated with impaired spinal mobility: a comparative study |
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Authors: | Gunnhild Berdal Silje Halvorsen Désirée van der Heijde Morten Mowe Hanne Dagfinrud |
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Affiliation: | (1) National Resource Center for Rehabilitation in Rheumatology, Diakonhjemmet Hospital, PO Box 23, Vinderen, No-0319 Oslo, Norway;(2) Department of Health Sciences, Faculty of Medicine, University of Oslo, PO Box 1089, Blindern, No-0318 Oslo, Norway;(3) Department of Physiotherapy, Medical Clinic, Oslo University Hospital, PO Box 4956, Nydalen, No-0424 Oslo, Norway;(4) Department of Rheumatology, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, the Netherlands;(5) Department of General Internal Medicine, Oslo University Hospital, PO Box 4959, Nydalen, No-0424 Oslo, Norway;(6) Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, PO Box 4959, Nydalen, No-0424 Oslo, Norway |
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Abstract: | Introduction Pulmonary involvement is a known manifestation in patients with ankylosing spondylitis (AS). However, previous studies have been based on small samples and the reported prevalence and associations with typical clinical features vary. The purpose of this study was to compare pulmonary function (PF) in patients with AS and population controls, and to study associations between PF and disease related variables, cardio-respiratory fitness and demographic variables in patients with AS. |
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