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Optogenetic in vivocell manipulation in KillerRed-expressing zebrafish transgenics
Authors:Cathleen Teh  Dmitry M Chudakov  Kar-Lai Poon  Ilgar Z Mamedov  Jun-Yan Sek  Konstantin Shidlovsky  Sergey Lukyanov  Vladimir Korzh
Affiliation:(1) Cancer and Developmental Cell Biology Division, Institute of Molecular and Cell Biology, A-STAR, Singapore;(2) Shemiakin and Ovchinnikov Institute of Bioorganic Chemistry RAS, Moscow, Russia;(3) Department of Biological Sciences, National University of Singapore, Singapore
Abstract:

Background  

KillerRed (KR) is a novel photosensitizer that efficiently generates reactive oxygen species (ROS) in KR-expressing cells upon intense green or white light illumination in vitro, resulting in damage to their plasma membrane and cell death.
Keywords:
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