WAMI: a web server for the analysis of minisatellite maps |
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| Authors: | Mohamed Abouelhoda Mohamed El-Kalioby Robert Giegerich |
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| Institution: | (1) Center for Informatics Sciences, Nile University, Giza, Egypt;(2) Systems and Biomedical Engineering Department, Faculty of Engineering, Cairo University, Giza, Egypt;(3) Practical Computer Science Department, Faculty of Technology, Bielefeld University, Bielefeld, Germany |
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| Abstract: | Background Minisatellites are genomic loci composed of tandem arrays of short repetitive DNA segments. A minisatellite map is a sequence
of symbols that represents the tandem repeat array such that the set of symbols is in one-to-one correspondence with the set
of distinct repeats. Due to variations in repeat type and organization as well as copy number, the minisatellite maps have
been widely used in forensic and population studies. In either domain, researchers need to compare the set of maps to each
other, to build phylogenetic trees, to spot structural variations, and to study duplication dynamics. Efficient algorithms
for these tasks are required to carry them out reliably and in reasonable time. |
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