Effect of undecanoic acid on germination of microconidia of wild and undecanoic acid resistant mutant of trichophyton rubrum

Effects of undecanoic acid (UDA) on germination of microconidia and elongation of germ tubes in UDA sensitive (uda _s) wild type Trichophyton rubrum and UDA resistant (uda _r) mutant derived from it, were studied. UDA inhibited conidial germination of uda _s and uda _r strains at 30 g/ml and 120 g/ml respectively which were minimum inhibitory concentrations of UDA for these two strains. When spores from both uda _s and uda _r were germinated in presence of subinhibitory concentration of UDA, germ tube growth was short. The elongation of germ tubes of spores pregerminated in absence of UDA was also inhibited by dose of UDA not sufficient to inhibit germination.