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Long‐term reversal of diabetes in non‐obese diabetic mice by liver‐directed gene therapy
Authors:Binhai Ren  Bronwyn A. O'Brien  Michelle R. Byrne  Edwin Ch'ng  Prudence N. Gatt  M. Anne Swan  Najah T. Nassif  Ming Q. Wei  Rik Gijsbers  Zeger Debyser  Ann M. Simpson
Affiliation:1. School of Medical & Molecular Biosciences, University of Technology Sydney, , Sydney, Australia;2. School of Medical Sciences (Anatomy & Histology) and Bosch Institute, University of Sydney, , Sydney, Australia;3. Griffith Health Institute and School of Medical Science, Griffith University, , Gold Coast, Southport, Australia;4. Laboratory for Molecular Virology & Gene Therapy, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, , Flanders, Belgium
Abstract:
Keywords:autoimmune diabetes  furin‐cleavable insulin  gene therapy  lentiviral vector  non‐obese diabetic mice  normal glucose tolerance
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