Characterization of the smtA gene encoding an S-adenosylmethionine-dependent methyltransferase of Escherichia coli |
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| Authors: | Kunitoshi Yamanaka Teru Ogura Hironori Niki Sota Hiraga |
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| Institution: | Department of Molecular Cell Biology, Institute of Molecular Embryology and Genetics, Kumamoto University School of Medicine, Kuhonji 4-24-1, Kumamoto 862, Japan |
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| Abstract: | Abstract The mukB operon is located at 21 min on the Escherichia coli chromosome and seems to consist of four genes, orf30 ( smtA ), mukF , mukE , and mukB . Based on sequence similarity, the promoter-proximal gene, orf30 ( smtA ), could encode an S-adenosylmethionine-dependent methyltransferase. The smtA gene is not essential for cell growth and its expression is positively regulated by H-NS, an Escherichia coli histone-like protein. |
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| Keywords: | Escherichia coli smtA Methyltransferase H-NS Curved DNA |
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