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Fibrinogen-like Protein 1 Is a Major Immune Inhibitory Ligand of LAG-3
Authors:Jun Wang  Miguel F. Sanmamed  Ila Datar  Tina Tianjiao Su  Lan Ji  Jingwei Sun  Ling Chen  Yusheng Chen  Gefeng Zhu  Weiwei Yin  Linghua Zheng  Ting Zhou  Ti Badri  Sheng Yao  Shu Zhu  Agedi Boto  Mario Sznol  Ignacio Melero  Lieping Chen
Affiliation:1. Department of Immunobiology, Yale University, New Haven, CT 06511, USA;2. Department of Pathology, Yale University, New Haven, CT 06510, USA;3. Immunotherapy Institute, Fujian Medical University, Fuzhou, Fujian 350108, China;4. Provincial Clinical Medical College, Fujian Medical University, Fuzhou, Fujian 350108, China;5. Key Laboratory for Biomedical Engineering of Ministry of Education, College of Biomedical Engineering and Instrument Science, Zhejiang University, Hangzhou 310027, China;6. Department of Medicine (Medical Oncology), Yale University, New Haven, CT 06510, USA;7. Department of Immunology and Immunotherapy, University of Navarra, Pamplona 31008, Spain;8. Department of Immunology, University of Pittsburgh, Pittsburgh, PA 15213, USA;9. Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA 15232, USA
Abstract:
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  • Keywords:cancer  immunology  immunotherapy  tumor immune-evasion mechanism  LAG-3  FGL1
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