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Methotrexate Chemotherapy Induces Persistent Tri-glial Dysregulation that Underlies Chemotherapy-Related Cognitive Impairment
Authors:Erin M Gibson  Surya Nagaraja  Alfonso Ocampo  Lydia T Tam  Lauren S Wood  Praveen N Pallegar  Jacob J Greene  Anna C Geraghty  Andrea K Goldstein  Lijun Ni  Pamelyn J Woo  Ben A Barres  Shane Liddelow  Hannes Vogel  Michelle Monje
Institution:1. Department of Neurology and Neurological Sciences, Stanford University, Palo Alto, CA 94305, USA;2. Department of Neurobiology, Stanford University, Palo Alto, CA 94305, USA;3. Department of Neuroscience and Physiology, NYU Neuroscience Institute, New York University School of Medicine, New York, NY 10016, USA;4. Department of Pathology, Stanford University, Palo Alto, CA 94305, USA;5. Department of Pediatrics, Stanford University, Palo Alto, CA 94305, USA;6. Department of Psychiatry and Behavioral Sciences, Stanford University, Palo Alto, CA 94305, USA;7. Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Palo Alto, CA 94305, USA
Abstract:
Keywords:chemotherapy  chemobrain  chemotherapy-related cognitive impairment  OPC  oligodendrocyte  myelin  astrocyte  microglia
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