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Indigenous Case of Disseminated Histoplasmosis from the <Emphasis Type="Italic">Penicillium marneffei</Emphasis> Endemic Area of China |
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| Authors: | Cunwei Cao Glenn Bulmer Jushang Li Ling Liang Youkun Lin Yongjia Xu Qinghua Luo |
| Institution: | (1) Department of Dermatology, The First Affiliated Hospital of Guangxi Medical University, 530021 Nanning, Guangxi Province, People’s Republic of China;(2) Department of Dermatology, First Hospital, Xinjiang Medical University, No. 1 Liyusham Road, 830000 Urumqi City, Xinjiang Province, People’s Republic of China |
| Abstract: | This is the first indigenous case of disseminated histoplasmosis reported from the Penicillium marneffei endemic area in southern China. It was diagnosed by histopathology of tissue, gross and microscopic morphology of the culture and PCR assay of the isolated fungus. Successful antifungal treatment was with itraconazole 400 mg/day for 5 months. This case suggests that histoplasmosis should be an important differential diagnosis in immunocompromised patients in southern China and South East Asia (the only endemic area for P. marneffei). |
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