The pharmacokinetic profile of a novel fixed-dose combination tablet of ibuprofen and paracetamol |
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| Authors: | Trevor Tanner Sue Aspley Andrew Munn Tracy Thomas |
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| Affiliation: | (1) Simbec Research Ltd, Cardiff Road, CF48 4DR Merthyr Tydfil, UK;(2) Reckitt Benckiser Healthcare UK Ltd, Dansom Lane, HU8 7DS Hull, Yorkshire, UK |
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| Abstract: | Background Ibuprofen and paracetamol differ in their mode of action and related therapeutic effects, suggesting that combined administration may offer improved analgesia. Reported here are the results of two studies on the pharmacokinetic properties of a novel ibuprofen (200 mg) and paracetamol (500 mg) fixed-dose combination tablet. |
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