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Dynamic connectivity in the mitral cell-granule cell microcircuit |
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| Authors: | Egger Veronica Urban Nathaniel N |
| Affiliation: | 1. Chemnitz University of Technology, Institute for Machine Tools and Production Processes (IWP), Reichenhainer Str. 70. 09126 Chemnitz, Germany;2. Fraunhofer Institute for Machine Tools and Forming Technology (IWU), Reichenhainer Str. 88. 09126 Chemnitz, Germany;1. Institut Langevin, ESPCI ParisTech, CNRS UMR7587, Inserm U979, Université Paris Diderot 7, 1 rue Jussieu, 75005 Paris, France;2. Laboratoire d''Imagerie et Modélisation en Neurobiologie et Cancérologie, CNRS UMR8165, Université Paris Diderot 7 et Université Paris Sud, 91405 Orsay France |
| Abstract: | The interactions between excitatory mitral cells and inhibitory granule cells are critical for the regulation of olfactory bulb activity. Here we review anatomical and physiological data on the mitral cell-granule cell circuit and provide a quantitative estimate of how this connectivity varies as a function of distance between mitral cells. We also discuss the ways in which the functional connectivity can be altered rapidly during olfactory bulb activity. |
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