| 酰基转移酶研究 |
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| 引用本文： | 范东东,孙铭娟,王梁华,焦炳华. 酰基转移酶研究[J]. 生命的化学, 2008, 28(6) |
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| 作者姓名： | 范东东 孙铭娟 王梁华 焦炳华 |
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| 作者单位： | 第二军医大学基础部生物化学与分子生物学教研室,上海,200433 |
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| 摘 要： | 酰基转移酶(acyltransferase)是一个多功能蛋白质大家族,在机体内组蛋白酰基转移酶、N-乙酰转移酶、胆固醇酰基转移酶等对维持机体正常功能与疾病发生都密切相关,研究其功能与机制对于疾病的发病机理与临床治疗具有重要意义.
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| 关 键 词： | 酰基转移酶 N-乙酰基转移酶 组蛋白乙酰转移酶 胆固醇酰基转移酶 |
Advance in study of acyltransferase |
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| Dong-Dong FAN,Ming-Juan SUN,Liang-Hua WANG,Bing-Hua JIAO. Advance in study of acyltransferase[J]. Chemistry of Life, 2008, 28(6) |
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| Authors: | Dong-Dong FAN Ming-Juan SUN Liang-Hua WANG Bing-Hua JIAO |
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| Affiliation: | Dong-Dong FAN Ming-Juan SUN Liang-Hua WANG Bing-Hua JIAO (Department of Biochemistry , Molecular Biology,College of Basic Medical Sciences,SMMU,Shanghai 200433,China) |
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| Abstract: | Acyltransferase, a multifunctional protein family, plays an important role in maintaining the normal function of cells. The family members include histone acetylase (HAT), histone deacetylase (HDAC), cholesterol acyltransferase (ACAT), and so on. It is important to study their functions and mechanism for the therapy of related diseases. |
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| Keywords: | acyltransferase N-acetyltransferase histone acetylase cholesterol acyltransferase |
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