Cytogenetic effects of UV laser radiation with wavelengths of 248, 223 and 193 nm on mammalian cells

Ten hours after irradiation of mouse cornea with doses of 0.09 to 1.5 J/cm2 the incidence of cells with chromosome aberrations increased linearly with dose and amounted to 11.7% at 248 nm, 5.5% at 223 nm and 2.6% at 193 nm per 1 J/cm2. No induced chromosome aberrations occurred 72 hr following irradiation. Within the dose range from 3.0 to 18 J/cm2 the cytogenetic effect of radiation was less manifest than that with the doses mentioned above, the frequency of chromosome aberrations being independent of either wave length or radiation dose and amounted to 2.5 to 3.0%.