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Antiallergic drug desloratadine as a selective antagonist of 5HT2A receptor ameliorates pathology of Alzheimer's disease model mice by improving microglial dysfunction |
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| Authors: | Jian Lu Chuzhao Zhang Jianlu Lv Xialin Zhu Xingwu Jiang Weiqiang Lu Yin Lu Zongxiang Tang Jiaying Wang Xu Shen |
| Affiliation: | 1. Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica and State Key Laboratory Cultivation Base for TCM Quality and Efficacy, Nanjing University of Chinese Medicine, Nanjing China ; 2. Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai China |
| Abstract: | |
| Keywords: | 5HT2AR Alzheimer's disease desloratadine microglia neuroinflammation |