Microencapsulation of erythrocytes |
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Authors: | Michael V Sefton Richard L Broughton |
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Institution: | Department of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, Ontario, M5S 1A4 Canada |
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Abstract: | Human erythrocytes have been encapsulated in a polyacrylate membrane by a simple precipitation process. The encapsulated cells appeared to remain functional after encapsulation: the consumption of glucose and the ability to reversibly bind oxygen was unimpaired. Furthermore, storage at 4°C for almost 6 months had no effect on the P50 and n50 values. This is the first time to our knowledge that live mammalian cells have been encapsulated in a polymer other than alginate. |
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Keywords: | Encapsulation Erythrocyte Polyacrylate membrane |
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