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Exploration of deleterious single nucleotide polymorphisms in the components of human P bodies: An in silico approach
Authors:Thejaswini Venkatesh  Padmanaban S. Suresh
Affiliation:1. Department of Molecular Reproduction, Development and Genetics, Indian Institute of Science, Bangalore 560012, India;2. Centre for Biomedical Research, Vellore Institute of Technology University, Vellore 632014, India
Abstract:
Keywords:SNP, single nucleotide polymorphism   XRN1, 5&prime  -3&prime   exoribonuclease 1   DCP2, DCP2 decapping enzyme homolog [S. cerevisiae])   EDC3, enhancer of mRNA decapping 3 homolog [S. cerevisiae])   CPEB1, cytoplasmic polyadenylation element binding protein 1   STAU1, staufen, RNA binding protein, homolog 1 [Drosophila])   TRIM71, tripartite motif containing 71, E3 ubiquitin protein ligase   SIFT, sorting intolerant from tolerant   PANTHER, Protein ANalysis THrough Evolutionary Relationships   UTR, untranslated region   miRNA, micro ribonucleic acid   ns, non-synonymous   subPSEC, substitution position-specific evolutionary conservation   rs, reference SNP
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