Y-STR diversity and sex-biased gene flow among Caribbean populations |
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Authors: | Tanya M. Simms Marisil R. Wright Emanuel Martinez Maria Regueiro Quinn McCartney Rene J. Herrera |
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Affiliation: | 1. Department of Molecular and Human Genetics, College of Medicine, Florida International University, Miami, FL 33199, USA;2. Royal Bahamas Police Force, Forensic Laboratory, P. O. Box N-458, Nassau, Bahamas |
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Abstract: | In the present study, we report, for the first time, the allele and haplotype frequencies of 17 Y-STR (Y-filer) loci in the populations of Haiti, Jamaica and the Bahamas (Abaco, Eleuthera, Exuma, Grand Bahama, Long Island and New Providence). This investigation was undertaken to assess the paternal genetic structure of the abovementioned Caribbean islands. A total of 607 different haplotypes were identified among the 691 males examined, of which 537 (88.5%) were unique. Haplotype diversities (HD) ranged from 0.989 in Long Island to 1.000 in Grand Bahama, with limited haplotype sharing observed among these Caribbean collections. Discriminatory capacity (DC) values were also high, ranging from 79.1% to 100% in Long Island and Grand Bahama, respectively, illustrating the capacity of this set of markers to differentiate between patrilineal related individuals within each population. Phylogenetic comparison of the Bahamian, Haitian and Jamaican groups with available African, European, East Asian and Native American populations reveals strong genetic ties with the continental African collections, a finding that corroborates our earlier work using autosomal STR and Y-chromosome binary markers. In addition, various degrees of sex-biased gene flow exhibiting disproportionately higher European paternal (as compared to autosomal) influences were detected in all Caribbean islands genotyped except for Abaco and Eleuthera. We attribute the presence or absence of asymmetric gene flow to unique, island specific demographic events and family structures. |
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Keywords: | DC, discriminatory capacity dbmax, maximum diversity between two populations dwmin, minimum diversity within the population, FUH, fraction of unique haplotypes HD, haplotype diversity n, sample size ng/μl, nanograms per microliter MDS, multidimensional scaling mbmin, minimum matching probability between two populations mwmax, maximum matching probability within the population mwmin, minimum matching probability within the population NRY, non-recombining portion of the Y-chromosome SNP, single nucleotide polymorphism STR, short tandem repeat US, United States YHRD, Y-STR haplotype reference database Y-SNP, Y-chromosomal single nucleotide polymorpshism Y-STR, Y-chromosome short tandem repeat |
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