The 50th anniversary of gene therapy: Beginnings and present realities |
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Authors: | Waclaw Szybalski |
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Affiliation: | McArdle Laboratory, University of Wisconsin, Madison, WI 53706, USA |
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Abstract: | Applying my experience in microbial genetics, especially in the genetic transformation/transduction of Bacilus subtilis bacteria, I decided around 1956 to develop a similar system for eukaryotic, especially human cell cultures. I believed it would permit the development of clinical applications for replacing defective genes to treat or cure some of the genetic diseases. |
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