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Propofol lipidic infusion promotes resistance to antifungals by reducing drug input into the fungal cell |
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| Authors: | Sofia Costa-de-Oliveira Ricardo Araujo Ana Silva-Dias Cidália Pina-Vaz Acácio Gonçalves Rodrigues |
| Affiliation: | (1) Department of Microbiology, Faculty of Medicine, University of Porto, Porto, Portugal;(2) Department of Microbiology, Hospital S. Joo, Porto, Portugal;(3) Burn Unit, Department of Plastic and Reconstructive Surgery, Faculty of Medicine, University of Porto and Hospital S. Joo, Alameda Prof. Hernani Monteiro, 4200 Porto, Portugal |
| Abstract: | BackgroundThe administration of non-antifungal drugs during patient hospitalization might be responsible for discrepancies between in vitro and in vivo susceptibility to antifungals. Propofol is often administered to intensive care units as a sedative. |
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