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Comparative genomic analysis of the arthropod muscle myosin heavy chain genes allows ancestral gene reconstruction and reveals a new type of 'partially' processed pseudogene
Authors:Florian Odronitz  Martin Kollmar
Institution:1.Abteilung NMR basierte Strukturbiologie, Max-Planck-Institut für Biophysikalische Chemie,G?ttingen,Germany
Abstract:

Background  

Alternative splicing of mutually exclusive exons is an important mechanism for increasing protein diversity in eukaryotes. The insect Mhc (myosin heavy chain) gene produces all different muscle myosins as a result of alternative splicing in contrast to most other organisms of the Metazoa lineage, that have a family of muscle genes with each gene coding for a protein specialized for a functional niche.
Keywords:
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