Bufadienolides from Drimia robusta and Urginea epigea (Hyacinthaceae) |
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Authors: | Koorbanally Neil A Koorbanally Chantal Harilal Avinash Mulholland Dulcie A Crouch Neil R |
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Affiliation: | Natural Products Research Group, School of Pure and Applied Chemistry, University of KwaZulu-Natal, Durban 4041, South Africa. Koorbanally@nu.ac.za |
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Abstract: | Two bufadienolides, 6beta-acetoxy-3beta,8beta,14beta-trihydroxy-12-oxobufa-4,20,22-trienolide and 14beta-hydroxybufa-3,5,20,22-tetraenolide were isolated from the dichloromethane extract of the bulbs of Drimia robusta and the methanol extract of the bulbs of Urginea epigea, respectively. The bulbs of Drimia robusta also yielded several known compounds, 6beta-acetoxy-3beta,8beta,12beta,14beta-tetrahydroxybufa-4,20,22-trienolide (12beta-hydroxyscillirosidin) from the dichloromethane extract and three common aromatic acids, 4-hydroxy-3-methoxybenzoic acid, 3,4-dihydroxybenzoic acid, and trans-3-(4'-hydroxyphenyl)-2-propenoic acid from the ethyl acetate extract. |
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Keywords: | Drimia robusta Urginea epigea Hyacinthaceae Bufadienolides Bufatetraenolide 6β-Acetoxy-3β,8β,14β-trihydroxy-12-oxobufa-4,20,22-trienolide 6β-Acetoxy-3β,8β,12β,14β-tetrahydroxybufa-4,20,22-trienolide (12β-hydroxyscillirosidin) 14β-Hydroxybufa-3,5,20,22-tetraenolide 4-Hydroxy-3-methoxybenzoic acid 3,4-Dihydroxybenzoic acid trans-3-(4′-Hydroxyphenyl)-2-propenoic acid |
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