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Bufadienolides from Drimia robusta and Urginea epigea (Hyacinthaceae)
Authors:Koorbanally Neil A  Koorbanally Chantal  Harilal Avinash  Mulholland Dulcie A  Crouch Neil R
Institution:Natural Products Research Group, School of Pure and Applied Chemistry, University of KwaZulu-Natal, Durban 4041, South Africa. Koorbanally@nu.ac.za
Abstract:Two bufadienolides, 6beta-acetoxy-3beta,8beta,14beta-trihydroxy-12-oxobufa-4,20,22-trienolide and 14beta-hydroxybufa-3,5,20,22-tetraenolide were isolated from the dichloromethane extract of the bulbs of Drimia robusta and the methanol extract of the bulbs of Urginea epigea, respectively. The bulbs of Drimia robusta also yielded several known compounds, 6beta-acetoxy-3beta,8beta,12beta,14beta-tetrahydroxybufa-4,20,22-trienolide (12beta-hydroxyscillirosidin) from the dichloromethane extract and three common aromatic acids, 4-hydroxy-3-methoxybenzoic acid, 3,4-dihydroxybenzoic acid, and trans-3-(4'-hydroxyphenyl)-2-propenoic acid from the ethyl acetate extract.
Keywords:Drimia robusta  Urginea epigea  Hyacinthaceae  Bufadienolides  Bufatetraenolide  6β-Acetoxy-3β    14β-trihydroxy-12-oxobufa-4  20  22-trienolide  6β-Acetoxy-3β    12β  14β-tetrahydroxybufa-4  20  22-trienolide (12β-hydroxyscillirosidin)  14β-Hydroxybufa-3  5  20  22-tetraenolide  4-Hydroxy-3-methoxybenzoic acid  3  4-Dihydroxybenzoic acid  trans-3-(4′-Hydroxyphenyl)-2-propenoic acid
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