Delineation of VEGF-regulated genes and functions in the cervix of pregnant rodents by DNA microarray analysis |
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| Authors: | Chishimba N Mowa Tianbo Li Subrina Jesmin Hans G Folkesson Sharon E Usip Raymond E Papka Guichuan Hou |
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| Institution: | (1) Department of Biology, Appalachian State University, Rankin Science North Building N219, 572 River Street, 28608 Boone, NC, USA;(2) Departments of Integrative Medical Sciences, Northeastern Ohio Universities Colleges of Medicine and Pharmacy, PO Box 95, 4209 St. Rt. 44, 44272 Rootstown, Ohio, USA;(3) Department of Gene Diagnostics and Therapeutics, Research Institute, International Medical Center of Japan, Tokyo, 1-21-1 Toyama, 162-8655 Shinjuku-ku, Tokyo, Japan;(4) Departments of Neurobiology and Anatomy, Northeastern Ohio Universities Colleges of Medicine and Pharmacy, PO Box 95, 4209 St. Rt. 44, 44272 Rootstown, Ohio, USA |
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| Abstract: | Background VEGF-regulated genes in the cervices of pregnant and non-pregnant rodents (rats and mice) were delineated by DNA microarray
and Real Time PCR, after locally altering levels of or action of VEGF using VEGF agents, namely siRNA, VEGF receptor antagonist
and mouse VEGF recombinant protein. |
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