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Changes in the reproductive function and developmental phenotypes in mice following intramuscular injection of an activin betaA-expressing plasmid |
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| Authors: | Mi-Nyeu Kim Moon Nyeo Park Hoi Kyung Jung Chunghee Cho Kelly E Mayo Byung-Nam Cho |
| Affiliation: | (1) Department of Life Science/Research Center for Biopharmaceutical Lead Molecule, The Catholic University of Korea, Bucheon, 420-743, Korea;(2) Department of Life Science, Kwangju Institute of Science and Technology (K-JIST), Kwangju, Korea;(3) Department of Biochemistry, Molecular Biology and Cell Biology, Northwestern University, Evanston, Illinois 60208, USA |
| Abstract: | BackgroundThe TGF-beta family protein activin has numerous reported activities with some uncertainty in the reproductive axis and development. The precise roles of activin in in vivo system were investigated using a transient gain of function model. |
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