| 磁性氧化铁纳米颗粒及其磁共振成像应用 |
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| 引用本文： | 乔瑞瑞,贾巧娟,曾剑峰,高明远.磁性氧化铁纳米颗粒及其磁共振成像应用[J].生物物理学报,2011(4):272-288. |
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| 作者姓名： | 乔瑞瑞 贾巧娟 曾剑峰 高明远 |
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| 作者单位： | 中国科学院化学研究所; |
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| 基金项目： | “973”计划项目(2011CB935800); 国家自然科学基金项目(21003135,81090271,20820102035)~~ |
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| 摘 要： | 磁性氧化铁纳米颗粒在磁共振成像方面的应用,已经在全世界范围内得到了广泛的关注,相关研究也被各国科学家高度重视.目前,磁性氧化铁纳米颗粒正在从早期的基于被动识别的肝部磁共振造影,快速转向基于主动识别的磁共振分子影像应用.本文将围绕磁性氧化铁纳米颗粒的生物体内应用,着重介绍磁性纳米颗粒的制备及其在疾病诊断,尤其是在肿瘤早期...
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| 关 键 词： | 磁性氧化铁纳米颗粒 磁共振 分子影像探针 肿瘤 |
Magnetic Iron Oxide Nanoparticles and Their Applications in Magnetic Resonance Imaging |
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| QIAO Ruirui,JIA Qiaojuan,ZENG Jianfeng,GAO Mingyuan Institute of Chemistry,the Chinese Academy of Sciences,Beijing ,China.Magnetic Iron Oxide Nanoparticles and Their Applications in Magnetic Resonance Imaging[J].Acta Biophysica Sinica,2011(4):272-288. |
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| Authors: | QIAO Ruirui JIA Qiaojuan ZENG Jianfeng GAO Mingyuan Institute of Chemistry the Chinese Academy of Sciences Beijing China |
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| Institution: | QIAO Ruirui,JIA Qiaojuan,ZENG Jianfeng,GAO Mingyuan Institute of Chemistry,the Chinese Academy of Sciences,Beijing 100190,China |
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| Abstract: | Magnetic iron oxide nanoparticles have received great attention due to their applications as contrast agents for magnetic resonance imaging(MRI).Now,in vivo applications of iron oxide nanoparticles are gradually shifting from passive targeting mode,such as liver imaging,to active targeting mode,leading to the emerging of a new multidisciplinary field-Molecular Imaging.This review mainly discusses the synthesis of magnetic iron oxide nanoparticles and their MRI applications,especially in molecular imaging of... |
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| Keywords: | Magnetic iron oxide nanoparticles Magnetic resonance Molecular imaging probe Tumor |
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