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An inexpensive approach to improving data derived from single photon emission computed tomography
Affiliation:1. Department of Biological Systems Engineering, Washington State University, Pullman, WA, 99164, USA;2. Gene and Linda Voiland School of Chemical Engineering and Bioengineering, Pullman, WA, 99164, USA;3. Chemistry Department and Materials Science and Engineering Program, Pullman, WA, 99164, USA;4. Department of Physics and Astronomy, Washington State University, Pullman, WA, 99164, USA;5. Department of Chemistry, Washington State University, Pullman, WA, 99164, USA;6. Institute for Integrated Catalysis, Pacific Northwest National Laboratory, Richland, WA, 99352, USA;7. Bioproducts Sciences and Engineering Laboratory, Richland, WA, 99354, USA;1. Dept. of Public Health, William Paterson University of New Jersey, University Hall, Suite 359, Wayne, NJ, 07470, USA;2. Dept. of Communication Disorders and Sciences, William Paterson University of New Jersey, University Hall, Wayne, NJ, 07470, USA;3. Dept. of Mathematics, Lehman College, City University of New York, 250 Bedford Park Boulevard West, Bronx, NY, 10468, USA;1. Institute of Diabetes Research, Group Immune Tolerance Type 1 Diabetes, Helmholtz Diabetes Center at Helmholtz Zentrum München, Heidemannstrasse 1, 80939 Munich, Germany;2. Deutsches Zentrum für Diabetesforschung (DZD), Ingolstaedter Landstrasse 1, 85764 Munich-Neuherberg, Germany;3. Islet Biology Group (IBEx), Exeter Centre of Excellence in Diabetes (EXCEED), University of Exeter College of Medicine and Health, Exeter EX2 5DW, UK;4. Department of Internal Medicine II (Gastroenterology and Hepatology), Klinikum der Ludwig-Maximilians-Universität München, Munich, Germany;5. Division of Clinical Pharmacology, Department of Medicine IV, Ludwig-Maximilians-Universität München, 80337 Munich, Germany;1. State Key Laboratory of Pulp & Paper Engineering, South China University of Technology, Wushan Road, Tianhe District, Guangzhou 510640, China;2. College of Food Science and Engineering, Northwest A&F University, Taicheng Road, Yangling District, Xianyang 712100, China;1. State Key Laboratory of Water Environment Simulation, School of Environment, Beijing Normal University, Beijing 100875, PR China;2. School of Environment and Civil Engineering, Dongguan University of Technology, Dongguan, Guangdong 523808, PR China
Abstract:The issue of inadequate solid standards for correcting nonuniformity in single photon emission computed tomography was addressed. Controlled, complex, motion of commercially available cobalt-57 standards was found to enhance the perceived nonuniformity of the standard and to minimize the effects of any local flaws. This maneuver provides a better standard than a refillable liquid phantom without the problems inherent in radioactive liquid standards which include: phantom deformation, poor mixing, absence of retrospective verification, accidental contamination and substantial handling requirements.
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