Beating of myocardial cells in monolayer culture. Inhibition by phospholipase C and restoration by lysophosphatides |
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| Authors: | K Goshima |
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| Affiliation: | 1. Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA;2. Department of Biology, Graduate School of Science, Kobe University, Kobe 657-8501, Japan |
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| Abstract: | Single myocardial cells from embryonic mouse heart beat spontaneously and rhythmically in monolayer cultures. Phospholipase C inhibited the beating. This inhibition was reversed by addition of lysophosphatides (lysolecithin and lysophosphatidylethanolamine). |
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