Transmitter time: synaptic plasticity and metabolic memory in the hypothalamus |
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| Authors: | Spanswick David C Simonds Stephanie E Cowley Michael A |
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| Institution: | Monash Obesity & Diabetes Institute, Monash University, Clayton, Victoria, Australia 3800. |
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| Abstract: | Hunger elicits feeding behavior by activating Agouti-related peptide (AgRP) neurons. Two recent studies show how fasting, or the hunger hormone ghrelin, promote excitatory glutamate release onto AgRP neurons (Yang et?al., 2011) and increase postsynaptic glutamate receptor-mediated drive (Liu et?al., 2012). |
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