Making a beta-barrel: assembly of outer membrane proteins in Gram-negative bacteria |
| |
Authors: | Rigel Nathan W Silhavy Thomas J |
| |
Affiliation: | Department of Molecular Biology, Princeton University, Princeton, NJ 08544, United States. |
| |
Abstract: | The outer membrane (OM) of Gram-negative bacteria is an essential organelle that serves as a selective permeability barrier by keeping toxic compounds out of the cell while allowing vital nutrients in. How the OM and its constituent lipid and protein components are assembled remains an area of active research. In this review, we describe our current understanding of how outer membrane proteins (OMPs) are delivered to and then assembled in the OM of the model Gram-negative organism Escherichia coli. |
| |
Keywords: | |
本文献已被 ScienceDirect PubMed 等数据库收录! |