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Prevalence of insulin resistance in a young adult population. Relationship with weight status
Authors:M. Eloísa Rogero Blanco  M. Rosa Albañil Ballesteros  Magdalena Sánchez Martin  Alejandro Rabanal Basalo  Antonio Olivas Domínguez  Concepción García Lacalle
Affiliation:1. Endocrinology Unit, Universidade Federal do Vale do São Francisco, Petrolina, Brazil;2. Department of Nursery Graduation, Universidade Federal do Vale do São Francisco, Petrolina, Brazil;3. Universidade Federal do Vale do São Francisco, Petrolina, Brazil;4. Department of Fetal Medicine, Instituto de Medicina Integral Professor, Fernando Figueira, Recife, Brazil;5. Department of Fetal Medicine, Hospital Dom Malan, Petrolina, Brazil;6. Instituto de Medicina Integral Professor, Fernando Figueira, Recife, Brazil;7. Li Ka Shing Knowledge Institute, St. Michael’s Hospital, University of Toronto, Toronto ON;8. Departments of Medicine and Obstetrics and Gynecology, St. Michael’s Hospital, University of Toronto, Toronto ON;1. Total Healthcare Center, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea;2. Department of Anesthesiology and Pain Medicine, Sungkyunkwan University School of Medicine, Kangbuk Samsung Hospital, Seoul, Republic of Korea;3. Department of Physical Education, Graduate School, Sangji University, Wonju, Republic of Korea;4. Department of Family Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea;5. Department of Preventive Medicine, School of Medicine, Kyung Hee University, Seoul, Republic of Korea
Abstract:AimTo estimate the prevalence of insulin resistance using both the Homeostatic Model Assessment (HOMA) index and basal insulinemia, and to analyze its relationship to overweight, as measured by body mass index (BMI) and waist circumference (WC).Patients and methodsA series of 118 non-diabetic young adults aged 18 and 19 years attending a primary care health center were studied. They were contacted by telephone, and their BMI, WC, HOMA and basal insulinemia were measured, among other parameters.ResultsHOMA values ≥ P90 (HOMA ≥3.15) were found in 9.3% of the sample (50% in the obesity group). Insulinemia ≥ P90 (16,9) was found in 11%. Based on BMI, 17.8% were overweight (26.5% of men, 11.6% of women), and 6.8% were obese (6.1% of men, 7.2% of women). Based on WC, 5.71% were obese when waist was measured at the midpoint and 15.38%, when measured at the iliac crest. HOMA was found to be significantly correlated to weight increase, BMI, WC, systolic blood pressure, triglycerides, and blood glucose, while correlation was only found between insulinemia and increased WC and decreased high lipoprotein cholesterol (HDL) levels.ConclusionIn this young adult sample, increased BMI and WC were associated to increased insulin resistance. High HOMA values were found in 9.3% of subjects.
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