6-Bicyclopiperazinyl-1-arylsulfonylindoles and 6-bicyclopiperidinyl-1-arylsulfonylindoles derivatives as novel, potent, and selective 5-HT6 receptor antagonists |
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Authors: | Isaac M Slassi A Xin T MacLean N Wilson J McCallum K Wang H Demchyshyn L |
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Affiliation: | NPS Allelix Corp., Mississauga, ON, Canada. misaac@allelix.com |
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Abstract: | A novel series of 6-bicyclopiperazinyl-1-arylsulfonylindoles and 6-bicyclopiperidinyl-1-arylsulfonylindoles derivatives was synthesized and found to be potent and selective 5-HT6 receptor antagonists. |
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