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6-Bicyclopiperazinyl-1-arylsulfonylindoles and 6-bicyclopiperidinyl-1-arylsulfonylindoles derivatives as novel, potent, and selective 5-HT6 receptor antagonists
Authors:Isaac M  Slassi A  Xin T  MacLean N  Wilson J  McCallum K  Wang H  Demchyshyn L
Affiliation:NPS Allelix Corp., Mississauga, ON, Canada. misaac@allelix.com
Abstract:A novel series of 6-bicyclopiperazinyl-1-arylsulfonylindoles and 6-bicyclopiperidinyl-1-arylsulfonylindoles derivatives was synthesized and found to be potent and selective 5-HT6 receptor antagonists.
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