Involvement of Ca2+ in the development of ischemic disorders of myocardial contractile function |
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| Authors: | I. V. Shemarova V. P. Nesterov S. M. Korotkov K. V. Sobol’ |
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| Affiliation: | 1.Sechenov Institute of Evolutionary Physiology and Biochemistry,Russian Academy of Sciences,St. Petersburg,Russia |
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| Abstract: | The review addresses the role of Ca2+ ions in the development of ischemic disorders of myocardial contractility associated with changes in Ca2+ homeostasis in cardiomyocytes and mitochondrial Ca2+ overload. A special attention is paid to the analysis of intracellular signaling mechanisms activated during the development of ischemic and reperfusion injury of the myocardium. |
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