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Small regulatory non‐coding RNAs in bacteria: physiology and mechanistic aspects
Authors:Francis Repoila  Fabien Darfeuille
Institution:1. UR888 UBLO—INRA, Domaine de Vilvert—Bat. 222, 78352 Jouy‐en‐Josas, France;2. INSERM U869, 146 rue Léo Saignat, 33076 Bordeaux, France;3. Université Victor Segalen, 146 rue Léo Saignat, 33076 Bordeaux, France.
Abstract:Regulatory ncRNAs (non‐coding RNAs) adjust bacterial physiology in response to environmental cues. ncRNAs can base‐pair to mRNAs and change their translation efficiency and/or their stability, or they can bind to proteins and modulate their activity. ncRNAs have been discovered in several species throughout the bacterial kingdom. This review illustrates the diversity of physiological processes and molecular mechanisms where ncRNAs are key regulators.
Keywords:regulation  RNA duplex  RNA/protein interaction  RNA/RNA interaction  small non‐coding RNAs
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