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Manipulating the expression of SARP family regulator BulZ and its target gene product to increase tacrolimus production |
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| Authors: | Ma Dongxu Wang Cheng Chen Hong Wen Jianping |
| Affiliation: | 1.Key Laboratory of Systems Bioengineering (Ministry of Education), Tianjin University, Tianjin, 300072, People’s Republic of China ;2.SynBio Research Platform, Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), School of Chemical Engineering and Technology, Tianjin University, Tianjin, 300072, People’s Republic of China ; |
| Abstract: | Applied Microbiology and Biotechnology - Tacrolimus (FK506), an effective immunosuppressant, is widely used in the treatment of autoimmune diseases. In this study, we identified that BulZ, a... |
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