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Expressed sequence tag profiling identifies developmental and anatomic partitioning of gene expression in the mouse prostate
Authors:Denise?E?Abbott,Colin?Pritchard,Nigel?J?Clegg,Camari?Ferguson,Ruth?Dumpit,Robert?A?Sikes,Peter?S?Nelson  author-information"  >  author-information__contact u-icon-before"  >  mailto:pnelson@fhcrc.org"   title="  pnelson@fhcrc.org"   itemprop="  email"   data-track="  click"   data-track-action="  Email author"   data-track-label="  "  >Email author
Affiliation:(1) Division of Human Biology, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, Seattle, WA 98109, USA;(2) Laboratory for Cancer Ontogeny and Therapeutics, Department of Biological Sciences, University of Delaware, Newark, DE 19716, USA;(3) Division of Clinical Research, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, Seattle, WA 98109, USA;
Abstract:

Background  

The prostate gland is an organ with highly specialized functional attributes that serves to enhance the fertility of mammalian species. Much of the information pertaining to normal and pathological conditions affecting the prostate has been obtained through extensive developmental, biochemical and genetic analyses of rodent species. Although important insights can be obtained through detailed anatomical and histological assessments of mouse and rat models, further mechanistic explanations are greatly aided through studies of gene and protein expression.
Keywords:
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