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5-Amidinobenzo[b]thiophenes as dual inhibitors of factors IXa and Xa |
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| Authors: | Qiao Jennifer X Cheng Xuhong Modi Dilip P Rossi Karen A Luettgen Joseph M Knabb Robert M Jadhav Prabhakar K Wexler Ruth R |
| Affiliation: | Bristol-Myers Squibb Pharmaceutical Research Institute, PO Box 5400, Princeton, NJ 08543-5400, USA. jennifer.qiao@bms.com |
| Abstract: | Syntheses and SAR studies of 5-amidinobenzo[b]thiophene analogs provided compounds with low submicromolar factor IXa activity and equal or slightly better selectivity relative to factor Xa. |
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| 本文献已被 ScienceDirect PubMed 等数据库收录！ | |