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Integration of purinergic and angiotensin II receptor function in renal vascular responses and renal injury in angiotensin II-dependent hypertension
Authors:Franco  Martha  Pérez-Méndez  Oscar  Kulthinee  Supaporn  Navar  L Gabriel
Institution:1.Department of Nephrology, Renal Pathophysiology Laboratory, Instituto Nacional de Cardiología “Ignacio Chávez”, Juan Badiano No.1, 14080, Mexico City, DF, Mexico
;2.Department Molecular Biology, Instituto Nacional de Cardiología “Ignacio Chávez”, Mexico City, Mexico
;3.Department of Physiology and Hypertension and Renal Center, Tulane University School of Medicine, New Orleans, LA, USA
;4.Department of Cardiovascular and Thoracic Technology, Chulabhorn International College of Medicine, Thammasat University, Rangsit, Pathum Thani, Thailand
;
Abstract:Purinergic Signalling - Glomerular arteriolar vasoconstriction and tubulointerstitial injury are observed before glomerular damage occurs in models of hypertension. High interstitial ATP...
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