Sesquiterpene lactones from Inula montana L |
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| Authors: | González-Romero M A Villaescusa-Castillo L Díaz-Lanza A M |
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| Affiliation: | Departamento de Farmacología, Facultad de Farmacia, Universidad de Alcalá, Madrid, Spain. |
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| Abstract: | Aerial parts of Inula montana were investigated for its sesquiterpenoid composition. Five sesquiterpene lactones, isoinuviscolide, gaillardin, 1beta-hydroxy-3beta-acetoxy-eudesm-4(15), 11(13)-dien-12-8beta-olide, pulchellin-C and pulchellin-E were identified for the first time in this plant. One of them, 1beta-hydroxy-3beta-acetoxy-eudesm-4(15),11(13)-dien-1 2-8beta-olide, is a novel natural product. The structures of this compounds were established by 1D and 2D-NMR spectroscopy. |
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