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Elevated levels of pro-apoptotic p53 and its oxidative modification by the lipid peroxidation product, HNE, in brain from subjects with amnestic mild cognitive impairment and Alzheimer's disease
Authors:Cenini Giovanna  Sultana Rukhsana  Memo Maurizio  Butterfield D Allan
Institution:Department of Chemistry, Center of Membrane Sciences, and Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY 40506-0055, USA.
Abstract:
Keywords:mild cognitive impairment (MCI)  Alzheimer's disease (AD)  apoptosis  oxidative stress  4-hydroxynonenal  HNE  p53
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