Microbiological Characteristics of Medically Important
<Emphasis Type="Italic">Trichosporon</Emphasis> Species |
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| Authors: | Hou-Min?Li Hong-Tao?Du Wei?Liu Zhe?Wan Email author" target="_blank">Ruo-Yu?LiEmail author |
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| Institution: | (1) Department of Dermatology/Research Center of Medical Mycology, Peking University First Hospital, No. 8 Xishiku Street, 100034, Xicheng District, Beijing, PR China;(2) Department of Dermatology, Peking Union Medical College Hospital, 100730 Beijing, PR China;(3) Research Center of Medical Mycology, Peking University First Hospital, No. 8 Xishiku Street, Xicheng District, Beijing, China |
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| Abstract: | Trichosporon species are opportunistic pathogens associated with a high mortality rate in immunocompromised patients. Disseminated trichosporonosis
is uncommon but reports are increasing. In this study, using 16 stock clinical isolates of suspected Trichosporon species and 4 known Trichosporon strains, we investigated the morphology, physio-biochemistry, molecular biology and antifungal susceptibility characteristics
of these Trichosporon spp. and discovered that ITS sequence-based identification is a rapid and accurate identification alternative to most phenotypic
or physio- biochemical methods. In vitro antifungal susceptibility tests showed high amphotericin B, itraconazole and terbinafine
MIC value in these Trichosporon strains. |
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| Keywords: | antifungal susceptibility ITS sequencing Trichosporon trichosporonosis |
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