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DNA repair inhibition: a possible mechanism of action of co-carcinogens
Authors:D Gaudin  R S Gregg  K L Yielding
Affiliation:Laboratory of Molecular Biology, University of Alabama School of Medicine in Birmingham, Alabama USA
Abstract:Co-carcinogens with a wide diversity of chemical structure have the common property of inhibiting DNA repair replication in normal human lymphocytes. This evidence suggests that inhibition of DNA repair may be an important factor in the mechanism of action of co-carcinogens.
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