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Atomic models of de novo designed cc beta-Met amyloid-like fibrils |
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| Authors: | Steinmetz Michel O Gattin Zrinka Verel Rene Ciani Barbara Stromer Thusnelda Green Janelle M Tittmann Peter Schulze-Briese Clemens Gross Heinz van Gunsteren Wilfred F Meier Beat H Serpell Louise C Müller Shirley A Kammerer Richard A |
| Affiliation: | 1 Biomolecular Research, Structural Biology, Paul Scherrer Institut, CH-5232 Villigen PSI, Switzerland 2 Physical Chemistry, ETH Zurich, CH-8093 Zürich, Switzerland 3 Wellcome Trust Centre for Cell-Matrix Research, Faculty of Life Sciences, University of Manchester, Manchester M13 PT, United Kingdom 4 Department of Biochemistry, School of Life Sciences, University of Sussex, Falmer BN1 9QG, United Kingdom 5 M.E. Müller-Institute for Structural Biology, Biozentrum, University of Basel, CH-4056 Basel, Switzerland 6 Electron Microscopy ETH Zürich (EMEZ), ETH, CH-8093 Zürich, Switzerland 7 Swiss Light Source, Paul Scherrer Institut, CH-5232 Villigen, Switzerland |
| Abstract: | |
| Keywords: | CD, circular dichroism FD, fiber diffraction PBS, phosphate-buffered saline UV, ultraviolet TEM, transmission electron microscopy AFM, atomic force microscopy STEM, scanning transmission electron microscopy MPL, mass per length NMR, nuclear magnetic resonance REDOR, rotational echo double resonance MD, molecular dynamics RMSD, root-mean-square deviation TI, thermodynamic integration |
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