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Schistosoma mansoni: microfluorometric determination of circulating anodic antigen and antigen-antibody complexes in infected hamster serum |
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| Authors: | A M Deelder D P Van Dalen J G Van Egmond |
| Affiliation: | Department of Parasitology, Medical Center, University of Leiden, Rapenburg 33, Leiden, The Netherlands |
| Abstract: | In this study the applicability of the defined antigen substrate spheres (DASS) system for the detection of circulating anodic antigen (CAA) in experimental Schistosoma mansoni infections in hamsters and mice is described. Using the DASS system as an antibody-antigen-labeled antibody technique, CAA could be detected both as a free circulating antigen and as the antigen-component of circulating antigen-antibody complexes. |
| Keywords: | Trematode Blood fluke Immunofluorescence Defined antigen substrate spheres system DASS system Antigen Circulating anodic antigen CAA Antibodies Immune complexes Hamsters Mice Sheep |
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