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On the use of 2,1,3-benzothiadiazole derivatives as selective live cell fluorescence imaging probes |
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| Authors: | Felipe F.D. Oliveira Diego C.B.D. Santos Alexandre A.M. Lapis José R. Corrêa Alexandre F. Gomes Fabio C. Gozzo Paulo F. Moreira Virgínia C. de Oliveira Frank H. Quina Brenno A.D. Neto |
| Affiliation: | 1. Laboratory of Medicinal and Technological Chemistry, University of Brasília (IQ-UnB), Campus Universitário Darcy Ribeiro CEP 70904-970, PO Box 4478, Brasília, DF, Brazil;2. National Institute of Catalysis (INCT-Catalysis), Brazil;3. Universidade Federal do Pampa, Unipampa/Urcamp, Bagé, RS, Brazil;4. Institute of Chemistry, State University of Campinas, Brazil;5. Institute of Chemistry, USP, São Paulo, SP, Brazil |
| Abstract: | Newly designed 2,1,3-benzothiadiazole-containing fluorescent probes with four excited state intramolecular proton transfer (ESIPT) sites were successfully tested in live cell-imaging assays using a confluent monolayer of human stem-cells (tissue). All tested dyes were compared with the commercially available DAPI and gave far better results. |
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