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On the use of 2,1,3-benzothiadiazole derivatives as selective live cell fluorescence imaging probes |
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| Authors: | Felipe FD Oliveira Diego CBD Santos Alexandre AM Lapis José R Corrêa Alexandre F Gomes Fabio C Gozzo Paulo F Moreira Virgínia C de Oliveira Frank H Quina Brenno AD Neto |
| Institution: | 1. Laboratory of Medicinal and Technological Chemistry, University of Brasília (IQ-UnB), Campus Universitário Darcy Ribeiro CEP 70904-970, PO Box 4478, Brasília, DF, Brazil;2. National Institute of Catalysis (INCT-Catalysis), Brazil;3. Universidade Federal do Pampa, Unipampa/Urcamp, Bagé, RS, Brazil;4. Institute of Chemistry, State University of Campinas, Brazil;5. Institute of Chemistry, USP, São Paulo, SP, Brazil |
| Abstract: | Newly designed 2,1,3-benzothiadiazole-containing fluorescent probes with four excited state intramolecular proton transfer (ESIPT) sites were successfully tested in live cell-imaging assays using a confluent monolayer of human stem-cells (tissue). All tested dyes were compared with the commercially available DAPI and gave far better results. |
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