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Evidence for detection of rat P2X4 receptor expressed on cells by generating monoclonal antibodies recognizing the native structure
Authors:Igawa  Tatsuhiro  Kishikawa  Shuhei  Abe  Yoshito  Yamashita  Tomohiro  Nagai  Saki  Shiroishi  Mitsunori  Shinozaki  Chinatsu  Tanaka  Hiroyuki  Tozaki-Saitoh  Hidetoshi  Tsuda  Makoto  Inoue  Kazuhide  Ueda  Tadashi
Institution:1.Department of Protein Structure, Function and Design, Graduate School of Pharmaceutical Sciences, Kyushu University, Higashi-ku, Fukuoka, 812-8582, Japan
;2.Department of Global Health-Care, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan
;3.Department of Pharmacognosy Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan
;4.Department of Life Innovation, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan
;5.Department of Molecular and System Pharmacology, Graduate School of Pharmaceutical Sciences, Kyushu University, Higashi-ku, Fukuoka, 812-8582, Japan
;
Abstract:Purinergic Signalling - P2X purinergic receptors are ATP-driven ionic channels expressed as trimers and showing various functions. A subtype, the P2X4 receptor present on microglial cells is highly...
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